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KMID : 1143820130090020101
Anxiety and Mood
2013 Volume.9 No. 2 p.101 ~ p.105
The Comparison of the Short-Term Prognosis According to the Polarity of First Episode in Children and Adolescent with Bipolar Disorder : A Single Center Study
Kweon Kuk-Ju

Park Su-Bin
Lee Su-Min
Kim Jae-Won
Shin Min-Sup
Yoo Hee-Jeong
Cho Soo-Churl
Kim Bung-Nyun
Abstract
Objectives : This study was conducted to evaluate the association between first episode polarity of pediatric bipolar disorder and prognosis.

Methods : We analyzed the clinical records of 66 inpatient subjects with DSM-IV defined pediatric bipolar disorder. The patients were split into 2 groups according to the polarity of the illness onset [depressive onset (DO) vs. manic/hypomanic/mixed onset (MO)]. Clinical feature and prognosis were compared between the two groups of patients.
Results : In our sample, 68% of patients experienced a depressive onset. In DO patients, rates of suicidal attempt, episodic illness course and comorbid disruptive behavior disorder were higher than rates in MO patients.

Conclusion : Findings from this study suggest that polarity of illness onset may be useful in predicting the prognosis of pediatric bipolar disorder.
KEYWORD
Bipolar disorder, First episode polarity, Children and adolescents, Prognosis
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